The Radford Highlanders versus the Clemson Tigers is a game to see on the Thursday Big South college basketball slate that includes a lot of exciting contests. For all our picks against the spread, continue reading.

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Big South Picks ATS Today

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Pick: Radford +19.5 vs. Clemson

• Matchup: Radford Highlanders at Clemson Tigers
• Projected Favorite & Spread: Clemson by 15.5 points (Bet on BetMGM)
• Spread: Clemson -19.5
• Time: 7:00 PM ET
• Date: November 21
• TV Channel: ACC Network Extra

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Pick: Presbyterian +8.5 vs. SFA

• Matchup: Presbyterian Blue Hose at Stephen F. Austin Lumberjacks
• Projected Favorite & Spread: SFA by 3 points (Bet on BetMGM)
• Spread: SFA -8.5
• Time: 7:30 PM ET
• Date: November 21
• TV Channel: ESPN+
• Live Stream: ESPN+

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